![[Vanilla + DLC] Diseases Expanded](https://mods4.com/wp-content/uploads/2026/08/mod-56063-590401c52c-128x128.png)
[Vanilla + DLC] Diseases Expanded
Introducing Diseases Expanded for Oxygen Not Included
Prepare for a more challenging and immersive experience within the harsh environments of Oxygen Not Included with the Diseases Expanded mod. This comprehensive modification introduces a host of new germs and ailments, designed to inject fresh dangers and strategic considerations into your colony management. No longer will every biome offer the same level of safety; prepare to adapt your strategies as unique environmental threats emerge.
New Germs and Their Ailments
Diseases Expanded injects a variety of new afflictions that your duplicants can contract, each with distinct sources and consequences:
* **Bog Bug Infestation:** Originating from the humble Bog Bucket, this infestation causes minor, cumulative insect bites that can become dangerous over time. A Muddy Salve, crafted at the Apothecary, is your remedy.
* **Frost-Covered Skin:** Wheezeworts, usually a source of cold, can now inflict this ailment. Frost Shards make skin sensitive to temperature and reduce germ resistance. Recover with a soothing bath in a Sauna or Hot Tub.
* **Moomoza:** Gas Grass and NatGas Vents are the culprits behind this resilient germ. The disease leads to frequent, albeit floral-scented, flatulence, with a Sprouting Tablet from the Apothecary offering relief.
* **Everlasting Hunger:** Sap Trees and Saturn Critter Traps can spread this germ, causing duplicants to burn calories at an accelerated rate. A Sweet Sap Shot, prepared and administered, is the cure.
* **Sleeping Curse:** Spindly Grub Fruit carries this germ, causing random bouts of narcolepsy. Increasing farming skill, wearing an Atmosuit, or enjoying an Espresso can help manage its effects.
* **Alien Symbiote:** Comets introduce this peculiar germ. While it boosts attributes, it also induces stress. A special Alien Cure is required to fully recover.
* **Mutating Disease:** A dangerous consequence of curing other diseases, this virus can mutate and become more severe, especially with radiation exposure. Unstable Antivirals or the research at a Vaccine Apothecary are crucial for combating its progression.
* **Nanobot Enhancement:** A more benevolent addition, Medical Nanobots, manufactured in the Molecular Forge, can actively combat other diseases and offer beneficial buffs to your duplicants.
Expanded Colony Management Tools
To combat these new threats, Diseases Expanded also introduces vital new structures:
* **Germcatcher:** This device samples ambient germs, providing research points or materials for vaccines.
* **Vaccine Apothecary:** Utilizes radiation to weaken germ samples and create temporary immunity to specific diseases.
* **Shield Generator:** Emits a protective shield to reduce cosmic radiation, a key factor in mitigating Alien Goo infections.
This mod significantly broadens the scope of challenges in Oxygen Not Included, demanding careful planning and resource management to keep your colony healthy and productive.
![[Vanilla + DLC] Diseases Expanded — screenshot 1](https://mods4.com/wp-content/uploads/2026/08/mod-56063-a89197a810.png)
![[Vanilla + DLC] Diseases Expanded — screenshot 2](https://mods4.com/wp-content/uploads/2026/08/mod-56063-058388e730.png)
![[Vanilla + DLC] Diseases Expanded — screenshot 3](https://mods4.com/wp-content/uploads/2026/08/mod-56063-3cbdf42040.png)