The Binding of Isaac: Rebirth
Download the best The Binding of Isaac: Rebirth mods with fast, direct ZIP downloads. Discover gameplay overhauls, new characters, items, enemies, bosses, visual improvements, and quality-of-life mods, all updated regularly for the latest game versions.
![[REP/REP+] Unique Items Port Pack](https://mods4.com/wp-content/uploads/2026/07/mod-27873-bebe4d3333-480x300.png.webp)
[REP/REP+] Unique Items Port Pack
![[REP/REP+] Unique Items API](https://mods4.com/wp-content/uploads/2026/07/mod-27874-210ea7c745-480x300.gif)
1.2 MB
Updated
[REP/REP+] Unique Items API
Treasure Room Start
Completion Mark Reminder
![[AB+] Chargebars for Brimstone & Co](https://mods4.com/wp-content/uploads/2026/07/mod-27877-1b8856e39c.png.webp)
[AB+] Chargebars for Brimstone & Co
Neko Stoney Sprite
741 KB
Updated
Spirit Sword Synergies!
Soundtrack Menu
1.8 MB
Updated
Unique C-Section Fetuses!
162 KB
Updated
ReactionAPI
2.9 MB
Updated